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hemN coproporphyrinogen III dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948362, updated on 19-Sep-2024

Summary

Official Symbol
hemN
Official Full Name
coproporphyrinogen III dehydrogenase
Primary source
ECOCYC:EG11836
Locus tag
b3867
See related
ASAP:ABE-0012629
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3860; yihJ
Summary
Radical SAM superfamily. [More information is available at EcoGene: EG11836]. Escherichia coli contains two coproporphyrinogen III oxidases, one that is active under aerobic conditions, the hemF gene product, and one that is active under anaerobic conditions, the hemN gene product . [More information is available at EcoCyc: EG11836].
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Genomic context

Sequence:
NC_000913.3 (4052045..4053418)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Der GTPase-activating protein YihI Neighboring gene uncharacterized protein YshB Neighboring gene DNA-binding transcriptional dual regulator NtrC

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 4 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables coproporphyrinogen dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables coproporphyrinogen dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables coproporphyrinogen dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables coproporphyrinogen oxidase activity IEA
Inferred from Electronic Annotation
more info
 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coproporphyrinogen III dehydrogenase
NP_418303.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4052045..4053418
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418303.2 coproporphyrinogen III dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418303.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1V2GKR5, C3SJQ7
    Conserved Domains (1) summary
    PRK09249
    Location:4457
    PRK09249; coproporphyrinogen dehydrogenase