Format

Send to:

Choose Destination

dapE succinyl-diaminopimelate desuccinylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948313, updated on 6-May-2021

Summary

Gene symbol
dapE
Gene description
succinyl-diaminopimelate desuccinylase
Primary source
ASAP:ABE-0008142
Locus tag
b2472
See related
ECOCYC:EG10208
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2467; msgB
Summary
A dapE mutant is not in the Keio collection; DAP auxotrophs require added DAP to grow and since no DAP was added during mutant construction, no auxotrophic mutants were recovered; dapE is not an essential gene (Baba, 2006). dapE(msgB) is a multicopy suppressor of grpE(Ts). [More information is available at EcoGene: EG10208]. The Escherichia coli N-succinyl-L-diaminopimelate desuccinylase exists as a mixture of homodimers and homotetramers. [More information is available at EcoCyc: EG10208].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (2591607..2592734)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YpfM Neighboring gene putative reductase YffB Neighboring gene UPF0370 protein YpfN Neighboring gene esterase YpfH

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables cobalt ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables succinyl-diaminopimelate desuccinylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables succinyl-diaminopimelate desuccinylase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables succinyl-diaminopimelate desuccinylase activity IEA
Inferred from Electronic Annotation
more info
 
enables succinyl-diaminopimelate desuccinylase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell division site IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
succinyl-diaminopimelate desuccinylase
NP_416967.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2591607..2592734
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416967.1 succinyl-diaminopimelate desuccinylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416967.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AED7
    Conserved Domains (1) summary
    PRK13009
    Location:2375
    PRK13009; succinyl-diaminopimelate desuccinylase; Reviewed
Support Center