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wecE dTDP-4-dehydro-6-deoxy-D-glucose transaminase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948296, updated on 30-Jul-2025
Official Symbol
wecE
Official Full Name
dTDP-4-dehydro-6-deoxy-D-glucose transaminase
Primary source
ECOCYC:EG11456
Locus tag
b3791
See related
ASAP:ABE-0012384
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3783; fcnA; rff; rffA; yifI
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Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (3975146..3976276)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-N-acetyl-D-mannosamine dehydrogenase Neighboring gene dTDP-glucose 4,6-dehydratase 2 Neighboring gene glucose-1-phosphate thymidylyltransferase 2 Neighboring gene dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase Neighboring gene lipid IIIECA flippase Neighboring gene TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase Neighboring gene enterobacterial common antigen polymerase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12. Hwang BY, et al. Chem Biol, 2004 Jul. PMID 15271350
  2. Physical map location of the rffC and rffA genes of Escherichia coli. Barr K, et al. J Bacteriol, 1993 Sep. PMID 8366065, Free PMC Article
  3. Toxicity-based selection of Escherichia coli mutants for functional recombinant protein production: application to an antibody fragment. Belin P, et al. Protein Eng Des Sel, 2004 May. PMID 15252207
  4. Accumulation of the enterobacterial common antigen lipid II biosynthetic intermediate stimulates degP transcription in Escherichia coli. Danese PN, et al. J Bacteriol, 1998 Nov. PMID 9811644, Free PMC Article
  5. Nucleotide sequence of the Escherichia coli rfe gene involved in the synthesis of enterobacterial common antigen. Molecular cloning of the rfe-rff gene cluster. Meier-Dieter U, et al. J Biol Chem, 1992 Jan 15. PMID 1730666

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables dTDP-4-amino-4,6-dideoxygalactose transaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dTDP-4-amino-4,6-dideoxygalactose transaminase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables dTDP-4-amino-4,6-dideoxygalactose transaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables pyridoxal phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in enterobacterial common antigen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within enterobacterial common antigen biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in polysaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
dTDP-4-dehydro-6-deoxy-D-glucose transaminase
NP_418238.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3975146..3976276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418238.1 dTDP-4-dehydro-6-deoxy-D-glucose transaminase

    See identical proteins and their annotated locations for NP_418238.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2X1NUH5
    Conserved Domains (1) summary
    PRK11706
    Location:1 → 376
    PRK11706; TDP-4-oxo-6-deoxy-D-glucose transaminase; Provisional
Nucleotide Protein
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