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wzxE lipid IIIECA flippase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948294, updated on 22-Sep-2022

Summary

Gene symbol
wzxE
Gene description
lipid IIIECA flippase
Primary source
ASAP:ABE-0012386
Locus tag
b3792
See related
ECOCYC:EG11486
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3784; wzx; yifJ
Summary
WzxE is a "flippase" responsible for movement of lipid III (Fuc4NAc-ManNAcA-GlcNAc-P-P-undecaprenol) across the membrane bilayer . [More information is available at EcoCyc: EG11486].
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Genomic context

Sequence:
NC_000913.3 (3976278..3977528)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene glucose-1-phosphate thymidylyltransferase 2 Neighboring gene RffC Neighboring gene dTDP-4-dehydro-6-deoxy-D-glucose transaminase Neighboring gene TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase Neighboring gene enterobacterial common antigen polymerase Neighboring gene UDP-N-acetyl-D-mannosaminuronic acid transferase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables intramembrane lipid transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3976278..3977528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418239.1 lipid IIIECA flippase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418239.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AAA7
    Conserved Domains (1) summary
    PRK15099
    Location:1416
    PRK15099; lipid III flippase WzxE