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tnaB tryptophan:H(+) symporter TnaB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948220, updated on 19-Nov-2025
Official Symbol
tnaB
Official Full Name
tryptophan:H(+) symporter TnaB
Primary source
ECOCYC:EG11006
Locus tag
b3709
See related
ASAP:ABE-0012135
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3702; tnaP; trpP
Summary
HAAAP family. [More information is available at EcoGene: EG11006]. TnaB is one of three known transporters for tryptophan in Escherichia coli, the others being Mtr and AroP. [More information is available at EcoCyc: EG11006].
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Sequence:
NC_000913.3 (3890236..3891483)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tnaAB operon leader peptide Neighboring gene tryptophanase Neighboring gene efflux pump MdtL Neighboring gene DNA-binding transcriptional dual regulator YidZ Neighboring gene putative phosphopantetheinyl transferase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aromatic amino acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-tryptophan catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within amino acid transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
tryptophan:H(+) symporter TnaB

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3890236..3891483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418165.1 tryptophan:H(+) symporter TnaB

    See identical proteins and their annotated locations for NP_418165.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8T5Z985, A0A8T6BSR0
    Conserved Domains (1) summary
    PRK09664
    Location:1 → 415
    PRK09664; low affinity tryptophan permease TnaB
Nucleotide Protein
Heading Accession and Version

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