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tnaB tryptophan:H(+) symporter TnaB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948220, updated on 19-Sep-2024

Summary

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Official Symbol
tnaB
Official Full Name
tryptophan:H(+) symporter TnaB
Primary source
ECOCYC:EG11006
Locus tag
b3709
See related
ASAP:ABE-0012135
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3702; tnaP; trpP
Summary
HAAAP family. [More information is available at EcoGene: EG11006]. TnaB is one of three known transporters for tryptophan in Escherichia coli, the others being Mtr and AroP. [More information is available at EcoCyc: EG11006].
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Genomic context

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Sequence:
NC_000913.3 (3890236..3891483)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tnaAB operon leader peptide Neighboring gene tryptophanase Neighboring gene efflux pump MdtL Neighboring gene DNA-binding transcriptional dual regulator YidZ Neighboring gene putative phosphopantetheinyl transferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A copy of insertion element IS5 is present within tnaB in the Kohara library of Escherichia coli W3110. Kamath AV, et al. J Bacteriol, 1994 Mar. PMID 8113202, Free PMC Article
  2. Membrane transport. Oxender DL. Annu Rev Biochem, 1972. PMID 4570962
  3. Instruction of translating ribosome by nascent peptide. Gong F, et al. Science, 2002 Sep 13. PMID 12228716
  4. Inhibition of expression of the tryptophanase operon in Escherichia coli by extrachromosomal copies of the tna leader region. Gish K, et al. J Bacteriol, 1993 Jun. PMID 8501042, Free PMC Article
  5. Location of the gene for the low-affinity tryptophan-specific permease of Escherichia coli. Edwards RM, et al. Biochem J, 1982 May 15. PMID 7052072, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aromatic amino acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within amino acid transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in tryptophan catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tryptophan:H(+) symporter TnaB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3890236..3891483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418165.1 tryptophan:H(+) symporter TnaB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418165.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5Z985, A0A8T6BSR0
    Conserved Domains (1) summary
    PRK09664
    Location:1 → 415
    PRK09664; low affinity tryptophan permease TnaB
Nucleotide Protein
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