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dnaA chromosomal replication initiator protein DnaA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948217, updated on 11-Oct-2018

Summary

Gene symbol
dnaA
Gene description
chromosomal replication initiator protein DnaA
Primary source
EcoGene:EG10235
Locus tag
b3702
See related
ASAP:ABE-0012103; ECOCYC:EG10235
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3694
Summary
DnaA-ATP is the active form; DnaA-ADP is inactive; switching betwee the two forms modulates initiation activity. [More information is available at EcoGene: EG10235].

Genomic context

Sequence:
NC_000913.3 (3882326..3883729, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA repair protein RecF Neighboring gene beta sliding clamp Neighboring gene protein YsdD Neighboring gene 50S ribosomal subunit protein L34

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Two-component system, organism-specific biosystem (from KEGG)
    Two-component system, organism-specific biosystemTwo-component signal transduction systems enable bacteria to sense, respond, and adapt to changes in their environment or in their intracellular state. Each two-component system consists of a sensor ...
  • Two-component system, conserved biosystem (from KEGG)
    Two-component system, conserved biosystemTwo-component signal transduction systems enable bacteria to sense, respond, and adapt to changes in their environment or in their intracellular state. Each two-component system consists of a sensor ...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA replication origin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA replication origin binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA replication initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
chromosomal replication initiator protein DnaA

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3882326..3883729 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418157.1 chromosomal replication initiator protein DnaA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418157.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03004
    Conserved Domains (1) summary
    TIGR00362
    Location:6465
    DnaA; chromosomal replication initiator protein DnaA
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