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gyrB DNA gyrase subunit B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948211, updated on 10-Oct-2019

Summary

Gene symbol
gyrB
Gene description
DNA gyrase subunit B
Primary source
EcoGene:EG10424
Locus tag
b3699
See related
ASAP:ABE-0012093; ECOCYC:EG10424
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
acrB; cou; Cou; ECK3691; himB; hisU; hopA; nalC; parA; pcbA; pcpA
Summary
gyrB is an essential gene. [More information is available at EcoGene: EG10424]. The GyrB subunit of DNA gyrase is required for the ATPase activity of the enzyme. [More information is available at EcoCyc: EG10424].

Genomic context

Sequence:
NC_000913.3 (3877705..3880119, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sugar phosphatase YidA Neighboring gene conserved protein YidB Neighboring gene DNA repair protein RecF Neighboring gene beta sliding clamp

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA supercoiling activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA topoisomerase activity IEA
Inferred from Electronic Annotation
more info
 
DNA topoisomerase type II (ATP-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA topoisomerase type II (ATP-hydrolyzing) activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA topoisomerase type II (ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 
DNA-dependent ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA topological change IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA topological change IEA
Inferred from Electronic Annotation
more info
 
DNA topological change IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA-dependent DNA replication IEA
Inferred from Electronic Annotation
more info
 
response to antibiotic IEA
Inferred from Electronic Annotation
more info
 
response to drug IDA
Inferred from Direct Assay
more info
PubMed 
transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
DNA topoisomerase complex (ATP-hydrolyzing) IDA
Inferred from Direct Assay
more info
PubMed 
chromosome IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
DNA gyrase subunit B
YP_026241.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3877705..3880119 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026241.1 DNA gyrase subunit B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026241.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AES6
    Conserved Domains (1) summary
    PRK14939
    Location:1804
    gyrB; DNA gyrase subunit B; Provisional
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