U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gyrB DNA gyrase subunit B [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948211, updated on 2-May-2024

Summary

Gene symbol
gyrB
Gene description
DNA gyrase subunit B
Primary source
ASAP:ABE-0012093
Locus tag
b3699
See related
ECOCYC:EG10424
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
acrB; Cou; ECK3691; himB; hisU; hopA; nalC; parA; pcbA; pcpA
Summary
gyrB is an essential gene. [More information is available at EcoGene: EG10424]. The GyrB subunit of DNA gyrase is required for the ATPase activity of the enzyme. [More information is available at EcoCyc: EG10424].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (3877705..3880119, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sugar phosphatase YidA Neighboring gene DUF937 domain-containing protein YidB Neighboring gene recombination mediator protein RecF Neighboring gene beta sliding clamp

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP-dependent activity, acting on DNA IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables DNA negative supercoiling activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA topoisomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within DNA topological change IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in chromosome organization IEA
Inferred from Electronic Annotation
more info
 
involved_in response to antibiotic IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to xenobiotic stimulus IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
DNA gyrase subunit B
YP_026241.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3877705..3880119 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026241.1 DNA gyrase subunit B [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026241.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H2VCI1, A0A192CEW1, A0A6C9Q9K6, A0AA36L2J9, Q1R4N8
    Conserved Domains (1) summary
    PRK14939
    Location:1804
    gyrB; DNA gyrase subunit B; Provisional