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recF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948209, updated on 24-Aug-2024

Summary

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Official Symbol
recF
Primary source
ASAP:ABE-0012095
Locus tag
b3700
See related
ECOCYC:EG10828
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3692; uvrF
Summary
[More information is available at EcoCyc: EG10828].
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Genomic context

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Sequence:
NC_000913.3 (3880148..3881221, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF937 domain-containing protein YidB Neighboring gene DNA gyrase subunit B Neighboring gene beta sliding clamp Neighboring gene chromosomal replication initiator protein DnaA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RecF protein targeting to post-replication (daughter strand) gaps II: RecF interaction with replisomes. Henry C, et al. Nucleic Acids Res, 2023 Jun 23. PMID 37125644, Free PMC Article
  2. DNA repair: common approaches to fixing double-strand breaks. Hiom K. Curr Biol, 2009 Jul 14. PMID 19602417
  3. Analysis of involvement of the RecF pathway in p44 recombination in Anaplasma phagocytophilum and in Escherichia coli by using a plasmid carrying the p44 expression and p44 donor loci. Lin Q, et al. Infect Immun, 2006 Apr. PMID 16552034, Free PMC Article
  4. Recs preventing wrecks. Courcelle J. Mutat Res, 2005 Sep 4. PMID 16011837
  5. ATP hydrolysis and DNA binding by the Escherichia coli RecF protein. Webb BL, et al. J Biol Chem, 1999 May 28. PMID 10336423

See all (103) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RecF protein targeting to postreplication (daughter strand) gaps I: DNA binding by RecF and RecFR.
    Title: RecF protein targeting to postreplication (daughter strand) gaps I: DNA binding by RecF and RecFR.
  2. RecF protein targeting to post-replication (daughter strand) gaps II: RecF interaction with replisomes.
    Title: RecF protein targeting to post-replication (daughter strand) gaps II: RecF interaction with replisomes.
  3. The rarA gene as part of an expanded RecFOR recombination pathway: Negative epistasis and synthetic lethality with ruvB, recG, and recQ.
    Title: The rarA gene as part of an expanded RecFOR recombination pathway: Negative epistasis and synthetic lethality with ruvB, recG, and recQ.
  4. we used genetics and single-molecule fluorescence microscopy to investigate whether RecF and RecO function together, or separately, in live Escherichia coli cells. We identified conditions in which RecF and RecO functions are genetically separable.
    Title: RecFOR epistasis group: RecF and RecO have distinct localizations and functions in Escherichia coli.
  5. model in which the recA433 mutation selectively impairs RecA functions associated with the RecF pathway, while retaining the ability to carry out RecBCD pathway-mediated functions
    Title: RecA433 cells are defective in recF-mediated processing of disrupted replication forks but retain recBCD-mediated functions.
  6. Data show that UvrD and UvrD252 counteract RecQ, RecJ, and RecFOR at forks blocked in the rep mutant of Escherichia coli.
    Title: UvrD and UvrD252 counteract RecQ, RecJ, and RecFOR in a rep mutant of Escherichia coli.
  7. N-terminus verified by Edman degradation on mature peptide
    Title: Purification and preliminary characterization of the Escherichia coli K-12 recF protein.
  8. Our results suggest that two types of sbcB-sensitive RecF pathways can be distinguished in E. coli, one that is activated by the sbcB15 mutation and one that is activated by sbcB null mutations.
    Title: sbcB15 And DeltasbcB mutations activate two types of recf recombination pathways in Escherichia coli.
  9. the RecF sub-pathways accounting for about 2/3 of the recombinants in E.coli
    Title: Inactivation of recG stimulates the RecF pathway during lesion-induced recombination in E. coli.
  10. A p44 recombination intermediate of Anaplasma phagocytophila is recovered in an E. coli strain with active RecF recombination pathway but not in strains with deficient RecF pathway.
    Title: Analysis of involvement of the RecF pathway in p44 recombination in Anaplasma phagocytophilum and in Escherichia coli by using a plasmid carrying the p44 expression and p44 donor loci.
Submit: New GeneRIF Correction See all GeneRIFs (12)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
  
involved_in DNA synthesis involved in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within DNA synthesis involved in DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in SOS response IEA
Inferred from Electronic Annotation
more info
  
involved_in double-strand break repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in recombinational repair EXP
Inferred from Experiment
more info
 PubMed 
involved_in recombinational repair IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in response to UV EXP
Inferred from Experiment
more info
 PubMed 
acts_upstream_of_or_within response to UV IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
recombination mediator protein RecF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3880148..3881221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418155.1 recombination mediator protein RecF [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418155.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376Y026
    Conserved Domains (1) summary
    TIGR00611
    Location:1 → 355
    recf; recF protein
Nucleotide Protein
Heading Accession and Version

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