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nlpA lipoprotein-28 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948175, updated on 19-Nov-2025
Official Symbol
nlpA
Official Full Name
lipoprotein-28
Primary source
ECOCYC:EG10657
Locus tag
b3661
See related
ASAP:ABE-0011964
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3651
Summary
Pathogenicity island eip (EAEC strain 042) has inserted in the adjacent yicS-nepI intergenic region. [More information is available at EcoGene: EG10657]. NlpA is an inner membrane lipoprotein in Escherichia coli that has been shown to be non-essential for growth in Escherichia coli . [More information is available at EcoCyc: EG10657].
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Sequence:
NC_000913.3 (3839175..3839993, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative exporter SetC Neighboring gene putative transporter YicL Neighboring gene protein YicU Neighboring gene uncharacterized protein YicS Neighboring gene purine ribonucleoside exporter

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Repression of the inner membrane lipoprotein NlpA by Rns in enterotoxigenic Escherichia coli. Bodero MD, et al. J Bacteriol, 2007 Mar. PMID 17189357, Free PMC Article
  2. Lipoprotein 28, an inner membrane protein of Escherichia coli encoded by nlpA, is not essential for growth. Yamaguchi K, et al. J Bacteriol, 1988 Aug. PMID 2841301, Free PMC Article
  3. The nlpA lipoprotein gene is located near the selC tRNA gene on the Escherichia coli chromosome. Jin T, et al. J Bacteriol, 1992 Jun. PMID 1317383, Free PMC Article
  4. Outer membrane permeability of Escherichia coli K12: isolation, cloning and mapping of suppressors of a defined antibiotic-hypersensitive mutant. Qi SY, et al. Mol Gen Genet, 1991 Oct. PMID 1944231
  5. The ETT2 gene cluster, encoding a second type III secretion system from Escherichia coli, is present in the majority of strains but has undergone widespread mutational attrition. Ren CP, et al. J Bacteriol, 2004 Jun. PMID 15150243, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in D-methionine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in methionine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within methionine transport EXP
Inferred from Experiment
more info
 PubMed 
involved_in methionine transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
lipoprotein-28

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3839175..3839993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418117.1 lipoprotein-28

    See identical proteins and their annotated locations for NP_418117.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A779UF32, A0A8S7RK53
    Conserved Domains (1) summary
    PRK09861
    Location:1 → 272
    PRK09861; lipoprotein NlpA
Nucleotide Protein
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