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mtlR transcriptional repressor MtlR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948116, updated on 17-Jul-2025
Official Symbol
mtlR
Official Full Name
transcriptional repressor MtlR
Primary source
ECOCYC:EG11965
Locus tag
b3601
See related
ASAP:ABE-0011769
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3590
Summary
The MtlR regulator participates in controlling several genes involved in mannitol utilization. [More information is available at EcoCyc: EG11965].
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Sequence:
NC_000913.3 (3775572..3776159)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF3302 domain-containing protein YibI Neighboring gene mannitol-specific PTS enzyme IICBA component Neighboring gene mannitol-1-phosphate 5-dehydrogenase Neighboring gene protein YibT Neighboring gene DUF2810 domain-containing protein YibL

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The Pfam protein families database. Bateman A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681378, Free PMC Article
  2. The general PTS component HPr determines the preference for glucose over mannitol. Choe M, et al. Sci Rep, 2017 Feb 22. PMID 28225088, Free PMC Article
  3. Corrected sequence of the mannitol (mtl) operon in Escherichia coli. Jiang W, et al. Mol Microbiol, 1990 Nov. PMID 1964486
  4. DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. DeLisa MP, et al. J Bacteriol, 2001 Sep. PMID 11514505, Free PMC Article
  5. The mannitol repressor (MtlR) of Escherichia coli. Figge RM, et al. J Bacteriol, 1994 Feb. PMID 8300537, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Preferred Names
transcriptional repressor MtlR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3775572..3776159
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418058.1 transcriptional repressor MtlR

    See identical proteins and their annotated locations for NP_418058.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0A2RXV9, A0A5B9ADE0
    Conserved Domains (1) summary
    PRK11001
    Location:26 → 193
    mtlR; MltR family transcriptional regulator
Nucleotide Protein
Heading Accession and Version

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