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sgbH [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948098, updated on 11-Sep-2024

Summary

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Official Symbol
sgbH
Primary source
ECOCYC:EG12285
Locus tag
b3581
See related
ASAP:ABE-0011698
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3570; yiaQ
Summary
YiaQ is possibly involved in the utilization of L-dehydroascorbate (2,3-diketo-L-gulonate) (Yew, 2002). [More information is available at EcoGene: EG12285].
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Genomic context

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Sequence:
NC_000913.3 (3748577..3749239)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - membrane subunit Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein Neighboring gene L-xylulose kinase Neighboring gene putative L-xylulose 5-phosphate 3-epimerase Neighboring gene L-ribulose-5-phosphate 4-epimerase SgbE Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase. Yew WS, et al. Biochemistry, 2005 Feb 15. PMID 15697206
  2. Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: crystallographic evidence for a proton relay system in the active site of 3-keto-L-gulonate 6-phosphate decarboxylase. Wise EL, et al. Biochemistry, 2004 Jun 1. PMID 15157078
  3. Transporter's evolution and carbohydrate metabolic clusters. Plantinga TH, et al. Trends Microbiol, 2004 Jan. PMID 14700544
  4. Aerobic L-ascorbate metabolism and associated oxidative stress in Escherichia coli. Campos E, et al. Microbiology (Reading), 2007 Oct. PMID 17906139
  5. A rare 920-kilobase chromosomal inversion mediated by IS1 transposition causes constitutive expression of the yiaK-S operon for carbohydrate utilization in Escherichia coli. Badía J, et al. J Biol Chem, 1998 Apr 3. PMID 9525947

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 3-dehydro-L-gulonate-6-phosphate decarboxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3-dehydro-L-gulonate-6-phosphate decarboxylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 3-dehydro-L-gulonate-6-phosphate decarboxylase activity IEA
Inferred from Electronic Annotation
more info
  
enables carboxy-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables orotidine-5'-phosphate decarboxylase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' pyrimidine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in L-ascorbic acid catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within carbohydrate catabolic process IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
3-keto-L-gulonate-6-phosphate decarboxylase SgbH
NP_418038.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3748577..3749239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418038.1 3-keto-L-gulonate-6-phosphate decarboxylase SgbH [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418038.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5YKB5
    Conserved Domains (1) summary
    PRK13305
    Location:1 → 217
    sgbH; 3-keto-L-gulonate-6-phosphate decarboxylase UlaD
Nucleotide Protein
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