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yiaO 2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948091, updated on 4-Feb-2026
Official Symbol
yiaO
Official Full Name
2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein
Primary source
ECOCYC:EG12283
Locus tag
b3579
See related
ASAP:ABE-0011694
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3568
Summary
L-dehydroascorbate is also called 2,3-diketo-L-gulonate (2,3 DKG). [More information is available at EcoGene: EG12283]. [More information is available at EcoCyc: EG12283].
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Sequence:
NC_000913.3 (3746094..3747080)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - membrane subunit Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - membrane subunit Neighboring gene L-xylulose kinase Neighboring gene 3-keto-L-gulonate-6-phosphate decarboxylase SgbH Neighboring gene putative L-xylulose 5-phosphate 3-epimerase Neighboring gene L-ribulose-5-phosphate 4-epimerase SgbE

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Ascorbic acid and dehydroascorbic acid interconversion without net oxidation or reduction. Deutsch JC. Anal Biochem, 1997 Apr 5. PMID 9126371
  2. Gas chromatographic/mass spectrometric measurement of ascorbic acid and analysis of ascorbic acid degradation in solution. Deutsch JC. Methods Enzymol, 1997. PMID 9211252
  3. Ascorbic acid oxidation by hydrogen peroxide. Deutsch JC. Anal Biochem, 1998 Jan 1. PMID 9448835
  4. Spontaneous hydrolysis and dehydration of dehydroascorbic acid in aqueous solution. Deutsch JC. Anal Biochem, 1998 Jul 1. PMID 9657882
  5. Deletion of the yiaMNO transporter genes affects the growth characteristics of Escherichia coli K-12. Plantinga TH, et al. Microbiology (Reading), 2005 May. PMID 15870475

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in carbohydrate transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within carbohydrate transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to salt NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in regulation of single-species biofilm formation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
  
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3746094..3747080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418036.1 2,3-diketo-L-gulonate:Na(+) symporter - periplasmic binding protein

    See identical proteins and their annotated locations for NP_418036.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376WQT8
    Conserved Domains (1) summary
    cd13679
    Location:27 → 324
    PBP2_TRAP_YiaO_like; Substrate-binding domain of 2,3-diketo-L-gulonate-binding Tripartite ATP-independent Periplasmic transport system and related proteins; the type 2 periplasmic-binding protein fold
Nucleotide Protein
Heading Accession and Version

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