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plaR DNA-binding transcriptional repressor PlaR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948084, updated on 30-Jul-2025
Official Symbol
plaR
Official Full Name
DNA-binding transcriptional repressor PlaR
Primary source
ECOCYC:EG12278
Locus tag
b3574
See related
ASAP:ABE-0011677
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3563; yiaJ
Summary
YiaJ is a transcriptional repressor that negatively controls the expression of genes involved in the catabolism of the rare pentose l-lyxose . [More information is available at EcoCyc: EG12278].
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Sequence:
NC_000913.3 (3741684..3742532, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene valine--pyruvate aminotransferase Neighboring gene putative electron transport protein YsaA Neighboring gene 2,3-diketo-L-gulonate reductase Neighboring gene DUF386 domain-containing protein YiaL

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Deletion of the yiaMNO transporter genes affects the growth characteristics of Escherichia coli K-12. Plantinga TH, et al. Microbiology (Reading), 2005 May. PMID 15870475
  2. A rare 920-kilobase chromosomal inversion mediated by IS1 transposition causes constitutive expression of the yiaK-S operon for carbohydrate utilization in Escherichia coli. Badía J, et al. J Biol Chem, 1998 Apr 3. PMID 9525947
  3. Regulation of expression of the yiaKLMNOPQRS operon for carbohydrate utilization in Escherichia coli: involvement of the main transcriptional factors. Ibañez E, et al. J Bacteriol, 2000 Aug. PMID 10913096, Free PMC Article
  4. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article
  5. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional repressor PlaR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3741684..3742532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418031.1 DNA-binding transcriptional repressor PlaR

    See identical proteins and their annotated locations for NP_418031.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7H9S0U9
    Conserved Domains (1) summary
    COG1414
    Location:24 → 271
    IclR; DNA-binding transcriptional regulator, IclR family [Transcription]
Nucleotide Protein
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