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lhgD L-2-hydroxyglutarate dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948069, updated on 22-Aug-2021

Summary

Gene symbol
lhgD
Gene description
L-2-hydroxyglutarate dehydrogenase
Primary source
ASAP:ABE-0008756
Locus tag
b2660
See related
ECOCYC:EG12387
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2654; lhgO; ygaF
Summary
LhgO is an L-2-hydroxyglutarate oxidase that is probably involved with recovering alpha-ketoglutarate (Kalliri, 2008). [More information is available at EcoGene: EG12387]. LhgO is a L-2-hydroxyglutarate oxidase that contains an FAD cofactor which is not covalently attached. [More information is available at EcoCyc: EG12387].
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Genomic context

Sequence:
NC_000913.3 (2789982..2791250)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene glutarate hydroxylase GlaH Neighboring gene succinate-semialdehyde dehydrogenase (NADP(+)) GabD Neighboring gene 4-aminobutyrate aminotransferase GabT

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Process Evidence Code Pubs
acts_upstream_of_or_within L-lysine catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lysine catabolic process EXP
Inferred from Experiment
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
L-2-hydroxyglutarate dehydrogenase
NP_417146.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2789982..2791250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417146.2 L-2-hydroxyglutarate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417146.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P37339
    Conserved Domains (1) summary
    PRK11728
    Location:1393
    PRK11728; L-2-hydroxyglutarate oxidase
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