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gabT 4-aminobutyrate aminotransferase GabT [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948067, updated on 6-May-2021

Summary

Gene symbol
gabT
Gene description
4-aminobutyrate aminotransferase GabT
Primary source
ASAP:ABE-0008760
Locus tag
b2662
See related
ECOCYC:EG10361
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2656
Summary
4-aminobutyrate aminotransferase is the initial enzyme of the 4-aminobutyrate (GABA) degradation pathway . [More information is available at EcoCyc: EG10361].
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Genomic context

Sequence:
NC_000913.3 (2792735..2794015)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-2-hydroxyglutarate dehydrogenase Neighboring gene succinate-semialdehyde dehydrogenase (NADP(+)) GabD Neighboring gene 4-aminobutanoate:H(+) symporter Neighboring gene DNA-binding transcriptional repressor GlaR

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 4-aminobutyrate transaminase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 4-aminobutyrate transaminase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 4-aminobutyrate transaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables 4-aminobutyrate:2-oxoglutarate transaminase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 4-aminobutyrate:2-oxoglutarate transaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables 5-aminovalerate transaminase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 5-aminovalerate transaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables pyridoxal phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
4-aminobutyrate aminotransferase GabT
NP_417148.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2792735..2794015
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417148.1 4-aminobutyrate aminotransferase GabT [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417148.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P22256
    Conserved Domains (1) summary
    PRK08088
    Location:1425
    PRK08088; 4-aminobutyrate--2-oxoglutarate transaminase
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