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dppA dipeptide ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948062, updated on 9-Mar-2022

Summary

Gene symbol
dppA
Gene description
dipeptide ABC transporter periplasmic binding protein
Primary source
ASAP:ABE-0011576
Locus tag
b3544
See related
ECOCYC:EG10248
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
alu; dpp; ECK3531; fpp
Summary
DppA binds dipeptides and heme, and mediates chemotaxis to dipeptides through the Tap chemoreceptor. [More information is available at EcoGene: EG10248]. DppA is the periplasmic binding component of the dipeptide ABC transporter. [More information is available at EcoCyc: EG10248].
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Genomic context

Sequence:
NC_000913.3 (3706098..3707705, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene dipeptide ABC transporter membrane subunit DppC Neighboring gene dipeptide ABC transporter membrane subunit DppB Neighboring gene tRNA-Pro Neighboring gene phosphoethanolamine transferase EptB

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables dipeptide transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables heme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables peptide binding IDA
Inferred from Direct Assay
more info
PubMed 
enables peptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in anion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within chaperone-mediated protein folding IDA
Inferred from Direct Assay
more info
PubMed 
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
 
involved_in dipeptide transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in dipeptide transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within dipeptide transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within heme transport IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in peptide transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peptide transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive chemotaxis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
 
located_in outer membrane-bounded periplasmic space EXP
Inferred from Experiment
more info
PubMed 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dipeptide ABC transporter periplasmic binding protein
NP_418001.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3706098..3707705 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418001.1 dipeptide ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418001.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P23847
    Conserved Domains (1) summary
    cd08493
    Location:30519
    PBP2_DppA_like; The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold