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gadE DNA-binding transcriptional activator GadE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948023, updated on 6-May-2021

Summary

Gene symbol
gadE
Gene description
DNA-binding transcriptional activator GadE
Primary source
ASAP:ABE-0011475
Locus tag
b3512
See related
ECOCYC:EG11544
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3496; yhiE; yhiT
Summary
The 750 bp region upstream of gadE is termed the Sensory Integration Region and contains sites needed for the regulation of three promoters (P1, -124; P2, -324/317; P3, -566) by activators YdeO, GadX, an a proposed unknown MnmE-dependent regulator, as well as controlling activation by GadE, GadW and EvgA; no Crp regulation or shorter transcripts were observed (Sayed, 2009). [More information is available at EcoGene: EG11544]. GadE is involved in the resistance to low pH observed upon overexpression of evgA or ydeO . [More information is available at EcoCyc: EG11544].
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Genomic context

Sequence:
NC_000913.3 (3658366..3658893)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene acid-resistance membrane protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene multidrug efflux pump membrane fusion protein MdtE

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General protein information

Preferred Names
DNA-binding transcriptional activator GadE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3658366..3658893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417969.1 DNA-binding transcriptional activator GadE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417969.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P63204
    Conserved Domains (1) summary
    PRK05826
    Location:69104
    PRK05826; pyruvate kinase; Provisional
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