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arsB arsenite/antimonite:H(+) antiporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948011, updated on 23-Nov-2021

Summary

Gene symbol
arsB
Gene description
arsenite/antimonite:H(+) antiporter
Primary source
ASAP:ABE-0011437
Locus tag
b3502
See related
ECOCYC:EG12236
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
arsF; ECK3487
Summary
ArsB can function alone using PMF to drive transport, as is the case with the chromosomal ArsB, which lacks the ArsA ATPase; ArsB proteins can use ATP to drive efflux if ArsA is present. [More information is available at EcoGene: EG12236]. Based on sequence similarity with the R773-plasmid encoded arsenite resistance operon, ArsB is a transporter and ArsC is an arsenate reductase . [More information is available at EcoCyc: EG12236].
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Genomic context

Sequence:
NC_000913.3 (3648935..3650224)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional repressor ArsR Neighboring gene arsenate reductase Neighboring gene pseudo

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Process Evidence Code Pubs
acts_upstream_of_or_within antimonite transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in arsenite transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within arsenite transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in arsenite transport IEA
Inferred from Electronic Annotation
more info
 
involved_in response to arsenic-containing substance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
arsenite/antimonite:H(+) antiporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3648935..3650224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417959.4 Peptide Sequence

    See identical proteins and their annotated locations for NP_417959.4

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AB93
    Conserved Domains (1) summary
    PRK15445
    Location:2428
    PRK15445; arsenical efflux pump membrane protein ArsB
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