U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

hybF hydrogenase maturation protein HybF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948004, updated on 19-Sep-2024

Summary

Official Symbol
hybF
Official Full Name
hydrogenase maturation protein HybF
Primary source
ECOCYC:EG11804
Locus tag
b2991
See related
ASAP:ABE-0009818
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2985
Summary
Paralogous to hypA, which may have a regulatory role. [More information is available at EcoGene: EG11804]. The HybF protein is required for maturation of hydrogenase isozymes 1 and 2 and probably plays a role in the nickel cofactor insertion step . [More information is available at EcoCyc: EG11804].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (3139977..3140318, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene disulfide reductase/organic hydroperoxide reductase Neighboring gene hydrogenase maturation factor HybG Neighboring gene hydrogenase 2-specific chaperone Neighboring gene hydrogenase 2 maturation protease Neighboring gene hydrogenase 2 large subunit Neighboring gene hydrogenase 2 membrane subunit Neighboring gene hydrogenase 2 iron-sulfur protein

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metallochaperone activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nickel cation binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nickel cation binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nickel cation binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein maturation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein maturation IEA
Inferred from Electronic Annotation
more info
 
involved_in protein maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein modification process IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
hydrogenase maturation protein HybF

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3139977..3140318 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417465.1 hydrogenase maturation protein HybF [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417465.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6N0IM80
    Conserved Domains (1) summary
    PRK12380
    Location:1113
    PRK12380; hydrogenase/urease nickel incorporation protein