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hycB formate hydrogenlyase subunit HycB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948002, updated on 19-Sep-2024

Summary

Official Symbol
hycB
Official Full Name
formate hydrogenlyase subunit HycB
Primary source
ECOCYC:EG10475
Locus tag
b2724
See related
ASAP:ABE-0008950
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2719; hevB
Summary
FhlA regulon. [More information is available at EcoGene: EG10475]. HycB is thought to code for a subunit of hydrogenase 3, a peptide of the [4Fe-4S] ferredoxin type, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase . [More information is available at EcoCyc: EG10475].
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Genomic context

Sequence:
NC_000913.3 (2849238..2849849, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene formate hydrogenlyase subunit HycE Neighboring gene formate hydrogenlyase subunit HycD Neighboring gene formate hydrogenlyase subunit HycC Neighboring gene regulator of the transcriptional regulator FhlA Neighboring gene hydrogenase 3 nickel incorporation protein HypA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables 4 iron, 4 sulfur cluster binding RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in anaerobic electron transport chain IDA
Inferred from Direct Assay
more info
PubMed 
involved_in anaerobic respiration IDA
Inferred from Direct Assay
more info
PubMed 
involved_in formate oxidation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in glucose catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of formate dehydrogenase complex IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
formate hydrogenlyase subunit HycB
NP_417204.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2849238..2849849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417204.1 formate hydrogenlyase subunit HycB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417204.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376D3R9, A0A376MGR1
    Conserved Domains (1) summary
    cd10554
    Location:4167
    HycB_like; HycB, HydN and similar proteins