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nikE Ni(2(+)) ABC transporter ATP binding subunit NikE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947987, updated on 22-Jun-2021

Summary

Gene symbol
nikE
Gene description
Ni(2(+)) ABC transporter ATP binding subunit NikE
Primary source
ASAP:ABE-0011362
Locus tag
b3480
See related
ECOCYC:EG12079
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3464; hydC; hydD
Summary
Mutants display nickel-remediated formate hydrogen-lyase, hydrogenase, and hydrogenase-related fumarase defects. [More information is available at EcoGene: EG12079]. The NikABCDE ATP-dependent nickel (II) uptake system is a member of the ATP-Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG12079].
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Genomic context

Sequence:
NC_000913.3 (3617776..3618582)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene Ni(2(+)) ABC transporter periplasmic binding protein Neighboring gene Ni(2(+)) ABC transporter membrane subunit NikB Neighboring gene Ni(2(+)) ABC transporter membrane subunit NikC Neighboring gene Ni(2(+)) ABC transporter ATP binding subunit NikD Neighboring gene DNA-binding transcriptional repressor NikR Neighboring gene rhs element protein RhsB Neighboring gene PF15631 family protein YhhH

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ABC-type nickel transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables ABC-type nickel transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding ISM
Inferred from Sequence Model
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables nickel cation binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ni(2(+)) ABC transporter ATP binding subunit NikE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3617776..3618582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417937.1 Ni(2(+)) ABC transporter ATP binding subunit NikE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417937.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P33594
    Conserved Domains (1) summary
    PRK10419
    Location:1268
    nikE; nickel ABC transporter ATP-binding protein NikE
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