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livM branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947966, updated on 29-Sep-2023

Summary

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Gene symbol
livM
Gene description
branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM
Primary source
ASAP:ABE-0011287
Locus tag
b3456
See related
ECOCYC:EG10541
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3440
Summary
LivFGHMJ and LivFGHMK are two ATP-dependent high-affinity branched-chain amino acid transport system and are members of the ATP Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10541].
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Genomic context

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Sequence:
NC_000913.3 (3594203..3595480, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sn-glycerol 3-phosphate ABC transporter periplasmic binding protein Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH Neighboring gene L-leucine/L-phenylalanine ABC transporter periplasmic binding protein Neighboring gene PanD maturation factor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of livH, the structural gene encoding a component of the leucine transport system in Escherichia coli. Nazos PM, et al. J Bacteriol, 1986 May. PMID 3009409, Free PMC Article
  2. The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport. Landick R, et al. J Biol Chem, 1985 Jul 15. PMID 3891753
  3. Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli. Nazos PM, et al. J Bacteriol, 1985 Sep. PMID 2993238, Free PMC Article
  4. Lrp, a leucine-responsive protein, regulates branched-chain amino acid transport genes in Escherichia coli. Haney SA, et al. J Bacteriol, 1992 Jan. PMID 1729203, Free PMC Article
  5. The LIV-I/LS system as a determinant of azaserine sensitivity of Escherichia coli K-12. Koyanagi T, et al. FEMS Microbiol Lett, 2004 Aug 1. PMID 15268940

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-isoleucine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-phenylalanine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-valine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables branched-chain amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables branched-chain amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables branched-chain amino acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within L-valine transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in branched-chain amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
acts_upstream_of_or_within branched-chain amino acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in branched-chain amino acid transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within isoleucine transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within phenylalanine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phenylalanine transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM
NP_417913.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3594203..3595480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417913.1 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417913.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P22729
    UniProtKB/TrEMBL
    A0A6M9X2I4
    Conserved Domains (1) summary
    PRK11301
    Location:1 → 419
    livM; leucine/isoleucine/valine transporter permease subunit; Provisional
Nucleotide Protein
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