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livH branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947965, updated on 3-Dec-2024
Official Symbol
livH
Official Full Name
branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH
Primary source
ECOCYC:EG10538
Locus tag
b3457
See related
ASAP:ABE-0011290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3441; hrbB; hrbC; hrbD
Summary
LivFGHMJ and LivFGHMK are two ATP-dependent high-affinity branched-chain amino acid transport system and are members of the ATP Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10538].
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Sequence:
NC_000913.3 (3595477..3596403, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM Neighboring gene L-leucine/L-phenylalanine ABC transporter periplasmic binding protein Neighboring gene PanD maturation factor

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cloning and characterization of livH, the structural gene encoding a component of the leucine transport system in Escherichia coli. Nazos PM, et al. J Bacteriol, 1986 May. PMID 3009409, Free PMC Article
  2. Structural and functional analysis of cloned DNA containing genes responsible for branched-chain amino acid transport in Escherichia coli. Oxender DL, et al. Proc Natl Acad Sci U S A, 1980 Mar. PMID 6445555, Free PMC Article
  3. Genetic and biochemical studies of transport systems for branched-chain amino acids in Escherichia coli K-12: isolation and properties of mutants defective in leucine-repressible transport activities. Yamato I, et al. J Bacteriol, 1980 Oct. PMID 6998958, Free PMC Article
  4. Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli. Nazos PM, et al. J Bacteriol, 1985 Sep. PMID 2993238, Free PMC Article
  5. The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport. Landick R, et al. J Biol Chem, 1985 Jul 15. PMID 3891753

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-isoleucine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-isoleucine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables L-leucine transmembrane transporter activity EXP
Inferred from Experiment
more info
 PubMed 
enables L-leucine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-leucine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables L-phenylalanine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-phenylalanine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-valine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-valine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables branched-chain amino acid transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-alanine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-alanine transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-isoleucine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-leucine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-leucine import across plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in L-valine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-valine transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within branched-chain amino acid transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in branched-chain amino acid transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within isoleucine transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phenylalanine transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phenylalanine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phenylalanine transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 
Preferred Names
branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH
NP_417914.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3595477..3596403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417914.1 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417914.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376M2M7, A0A5B9ARQ6
    Conserved Domains (1) summary
    PRK10740
    Location:1 → 308
    PRK10740; high-affinity branched-chain amino acid ABC transporter permease LivH
Nucleotide Protein
Heading Accession and Version

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