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ugpQ glycerophosphodiester phosphodiesterase UgpQ [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947955, updated on 25-Jun-2025
Official Symbol
ugpQ
Official Full Name
glycerophosphodiester phosphodiesterase UgpQ
Primary source
ECOCYC:EG11050
Locus tag
b3449
See related
ASAP:ABE-0011264
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3433
Summary
Pho regulon. [More information is available at EcoGene: EG11050]. UgpQ is a cytosolic glycerophosphodiester phosphodiesterase with broad substrate specificity . [More information is available at EcoCyc: EG11050].
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Sequence:
NC_000913.3 (3587370..3588113, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative heat shock chaperone Neighboring gene glutathione hydrolase proenzyme Neighboring gene DUF2756 domain-containing protein YhhA Neighboring gene sn-glycerol 3-phosphate ABC transporter ATP binding subunit Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE Neighboring gene sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA Neighboring gene sn-glycerol 3-phosphate ABC transporter periplasmic binding protein

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity. Ohshima N, et al. J Bacteriol, 2008 Feb. PMID 18083802, Free PMC Article
  2. Nucleotide sequence of the ugpQ gene encoding glycerophosphoryl diester phosphodiesterase of Escherichia coli K-12. Kasahara M, et al. Nucleic Acids Res, 1989 Apr 11. PMID 2541415, Free PMC Article
  3. Uptake of glycerol-2-phosphate via the ugp-encoded transporter in Escherichia coli K-12. Yang K, et al. J Bacteriol, 2009 Jul. PMID 19429609, Free PMC Article
  4. Nucleotide sequence of the ugp genes of Escherichia coli K-12: homology to the maltose system. Overduin P, et al. Mol Microbiol, 1988 Nov. PMID 3062310
  5. Carbon-starvation induction of the ugp operon, encoding the binding protein-dependent sn-glycerol-3-phosphate transport system in Escherichia coli. Su TZ, et al. Mol Gen Genet, 1991 Nov. PMID 1745236

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that UgpQ has broad substrate specificity toward various glycerophosphodiesters, producing sn-glycerol-3-phosphate and the corresponding alcohols.
    Title: Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables glycerophosphocholine phosphodiesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycerophosphocholine phosphodiesterase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glycerophosphodiester phosphodiesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycerophosphodiester phosphodiesterase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glycerophosphoinositol glycerophosphodiesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycerophosphoinositol glycerophosphodiesterase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
glycerophosphodiester phosphodiesterase UgpQ
NP_417906.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3587370..3588113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417906.1 glycerophosphodiester phosphodiesterase UgpQ [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417906.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AN05
    Conserved Domains (1) summary
    PRK09454
    Location:1 → 247
    ugpQ; cytoplasmic glycerophosphodiester phosphodiesterase; Provisional
Nucleotide Protein
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