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glpE thiosulfate sulfurtransferase GlpE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947935, updated on 3-Jun-2026
Official Symbol
glpE
Official Full Name
thiosulfate sulfurtransferase GlpE
Primary source
ECOCYC:EG10395
Locus tag
b3425
See related
ASAP:ABE-0011182
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3411
Summary
glpE, yceA and yibN are paralogs. [More information is available at EcoGene: EG10395].
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Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (3561497..3561823, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator RtcR Neighboring gene pseudo Neighboring gene rhomboid protease GlpG Neighboring gene aerobic glycerol 3-phosphate dehydrogenase Neighboring gene putative uncharacterized protein YzgL

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Improved fermentative L-cysteine overproduction by enhancing a newly identified thiosulfate assimilation pathway in Escherichia coli. Kawano Y, et al. Appl Microbiol Biotechnol, 2017 Sep. PMID 28756590
  2. Biochemical and Genetic Characterization of PspE and GlpE, Two Single-domain Sulfurtransferases of Escherichia coli. Cheng H, et al. Open Microbiol J, 2008. PMID 19088907, Free PMC Article
  3. Multiple promoters are responsible for transcription of the glpEGR operon of Escherichia coli K-12. Yang B, et al. Biochim Biophys Acta, 1998 Mar 4. PMID 9524241
  4. Physical and genetic structure of the glpD-malT interval of the Escherichia coli K-12 chromosome. Identification of two new structural genes of the glp-regulon. Schweizer H, et al. Mol Gen Genet, 1986 Mar. PMID 3012272
  5. Regulation of glpD and glpE gene expression by a cyclic AMP-cAMP receptor protein (cAMP-CRP) complex in Escherichia coli. Choi YL, et al. Biochim Biophys Acta, 1991 Jan 17. PMID 1846566

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GlpE is therefore concluded to function in the novel CysM-independent thiosulfate assimilation pathway by catalyzing thiosulfate to sulfite.
    Title: Improved fermentative L-cysteine overproduction by enhancing a newly identified thiosulfate assimilation pathway in Escherichia coli.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables thiosulfate-cyanide sulfurtransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables thiosulfate-cyanide sulfurtransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables thiosulfate-cyanide sulfurtransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables thiosulfate-thioredoxin sulfurtransferase activity EXP
Inferred from Experiment
more info
 PubMed 
enables thiosulfate-thioredoxin sulfurtransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in sulfur utilization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within sulfur utilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
thiosulfate sulfurtransferase GlpE
NP_417883.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3561497..3561823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417883.1 thiosulfate sulfurtransferase GlpE

    See identical proteins and their annotated locations for NP_417883.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A192CDC9, A0AA36P9C8, Q1R5L0
    Conserved Domains (1) summary
    PRK00162
    Location:1 → 108
    glpE; thiosulfate sulfurtransferase GlpE
Nucleotide Protein
Heading Accession and Version

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