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glpD aerobic glycerol 3-phosphate dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947934, updated on 25-Jan-2024

Summary

Gene symbol
glpD
Gene description
aerobic glycerol 3-phosphate dehydrogenase
Primary source
ASAP:ABE-0011191
Locus tag
b3426
See related
ECOCYC:EG10394
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3412; glyD
Summary
LpxB and GlpD associate in vitro. [More information is available at EcoGene: EG10394]. The aerobic glycerol 3-phosphate dehydrogenase (GlpD) is a homodimeric enzyme associated with the cytoplasmic membrane through binding to negatively-charged phopholipids . [More information is available at EcoCyc: EG10394].
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Genomic context

Sequence:
NC_000913.3 (3562013..3563518)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene rhomboid protease GlpG Neighboring gene thiosulfate sulfurtransferase GlpE Neighboring gene putative uncharacterized protein YzgL Neighboring gene glycogen phosphorylase

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables FAD binding IDA
Inferred from Direct Assay
more info
PubMed 
enables electron transfer activity IDA
Inferred from Direct Assay
more info
PubMed 
enables glycerol-3-phosphate dehydrogenase (quinone) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables glycerol-3-phosphate dehydrogenase (quinone) activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in electron transport chain IEA
Inferred from Electronic Annotation
more info
 
involved_in glycerol catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glycerol-3-phosphate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within glycerol-3-phosphate catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in glycerol-3-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in organic substance metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
part_of glycerol-3-phosphate dehydrogenase complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of glycerol-3-phosphate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
aerobic glycerol 3-phosphate dehydrogenase
NP_417884.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3562013..3563518
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417884.1 aerobic glycerol 3-phosphate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417884.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827IMN8
    Conserved Domains (1) summary
    PRK12266
    Location:27501
    glpD; glycerol-3-phosphate dehydrogenase; Reviewed