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glgA glycogen synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947932, updated on 4-Feb-2026
Official Symbol
glgA
Official Full Name
glycogen synthase
Primary source
ECOCYC:EG10377
Locus tag
b3429
See related
ASAP:ABE-0011200
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3415
Summary
Glycogen synthase is a glycosyltransferase, the second enzyme in the glycogen biosynthesis pathway. [More information is available at EcoCyc: EG10377].
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Sequence:
NC_000913.3 (3566600..3568033, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative uncharacterized protein YzgL Neighboring gene glycogen phosphorylase Neighboring gene glucose-1-phosphate adenylyltransferase Neighboring gene limit dextrin alpha-1,6-glucohydrolase Neighboring gene 1,4-alpha-glucan branching enzyme

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Oligosaccharide binding in Escherichia coli glycogen synthase. Sheng F, et al. Biochemistry, 2009 Oct 27. PMID 19761218
  2. Biosynthesis of bacterial glycogen. Purification and properties of the Escherichia coli B ADPglucose:1,4-alpha-D-glucan 4-alpha-glucosyltransferase. Fox J, et al. Biochemistry, 1976 Feb 24. PMID 2288
  3. The 55-kilodalton protein in an oriC complex fraction is glycogen synthase. Kaidow A, et al. J Bacteriol, 1992 Aug. PMID 1644773, Free PMC Article
  4. Identification of lysine 15 at the active site in Escherichia coli glycogen synthase. Conservation of Lys-X-Gly-Gly sequence in the bacterial and mammalian enzymes. Furukawa K, et al. J Biol Chem, 1990 Feb 5. PMID 2105316
  5. Role of the conserved Lys-X-Gly-Gly sequence at the ADP-glucose-binding site in Escherichia coli glycogen synthase. Furukawa K, et al. J Biol Chem, 1993 Nov 15. PMID 8226921

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. No glycogen was found in the DeltaglgA and DeltaglgA DeltamalP strains grown on glucose.
    Title: Role of maltose enzymes in glycogen synthesis by Escherichia coli.
  2. N-terminus verified by Edman degradation on complete protein
    Title: The 55-kilodalton protein in an oriC complex fraction is glycogen synthase.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity IEA
Inferred from Electronic Annotation
more info
  
enables alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in glycogen biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycogen biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
glycogen synthase
NP_417887.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3566600..3568033 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417887.1 glycogen synthase

    See identical proteins and their annotated locations for NP_417887.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376FX40, A0A376TRF0
    Conserved Domains (1) summary
    PRK00654
    Location:1 → 476
    glgA; glycogen synthase GlgA
Nucleotide Protein
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