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glpR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947926, updated on 19-Feb-2025
Official Symbol
glpR
Primary source
ECOCYC:EG10400
Locus tag
b3423
See related
ASAP:ABE-0011176
Gene type
pseudo
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3409
Summary
The sn-Glycerol-3-phosphate repressor," GlpR, acts as the repressor of the glycerol-3-phosphate regulon, which is organized in different operons . [More information is available at EcoCyc: EG10400].
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Sequence:
NC_000913.3 (3559848..3560605, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene RNA-splicing ligase Neighboring gene DNA-binding transcriptional activator RtcR Neighboring gene rhomboid protease GlpG Neighboring gene thiosulfate sulfurtransferase GlpE

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Scalable method to determine mutations that occur during adaptive evolution of Escherichia coli. Raghunathan A, et al. Biotechnol Lett, 2003 Mar. PMID 12882568
  2. Repressor for the sn-glycerol-3-phosphate regulon of Escherichia coli K-12: cloning of the glpR gene and identification of its product. Schweizer H, et al. J Bacteriol, 1985 Feb. PMID 3881401, Free PMC Article
  3. Unexpected presence of defective glpR alleles in various strains of Escherichia coli. Holtman CK, et al. J Bacteriol, 2001 Feb. PMID 11157961, Free PMC Article
  4. Action at a distance for negative control of transcription of the glpD gene encoding sn-glycerol 3-phosphate dehydrogenase of Escherichia coli K-12. Yang B, et al. J Bacteriol, 1996 Dec. PMID 8955388, Free PMC Article
  5. Characterization of the interaction of the glp repressor of Escherichia coli K-12 with single and tandem glp operator variants. Zhao N, et al. J Bacteriol, 1994 Apr. PMID 8157609, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Recently identified mutations that are likely to cause loss of function of the glpR and crl genes, which may have serious implications for physiological experiments using the affected strains, are reported.
    Title: Newly identified genetic variations in common Escherichia coli MG1655 stock cultures.
  2. N-terminus verified by Edman degradation on complete protein
    Title: Repressor for the sn-glycerol 3-phosphate regulon of Escherichia coli K-12: primary structure and identification of the DNA-binding domain.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ligand-modulated transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  

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