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hofM DNA utilization protein HofM [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947908, updated on 3-Dec-2024
Official Symbol
hofM
Official Full Name
DNA utilization protein HofM
Primary source
ECOCYC:G7739
Locus tag
b3395
See related
ASAP:ABE-0011079
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3382; yrfD
Summary
hofM (yrfD)has been demonstrated to have a CRP-S promoter co-regulated by both Crp and Sxy (Cameron, 2006). [More information is available at EcoGene: EG12925]. The yrfD gene product is required for utilization of DNA as the sole source of carbon and energy; yrfD is homologous to genes involved in natural competence and genetic transformation in other bacteria . [More information is available at EcoCyc: G7739].
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Sequence:
NC_000913.3 (3521972..3522751, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA utilization protein HofQ Neighboring gene DNA utilization protein HofP Neighboring gene DNA utilization protein HofO Neighboring gene DNA utilization protein HofN Neighboring gene peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA Neighboring gene ADP-sugar diphosphatase NudE

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. PpdD type IV pilin of Escherichia coli K-12 can Be assembled into pili in Pseudomonas aeruginosa. Sauvonnet N, et al. J Bacteriol, 2000 Feb. PMID 10633126, Free PMC Article
  2. Non-canonical CRP sites control competence regulons in Escherichia coli and many other gamma-proteobacteria. Cameron AD, et al. Nucleic Acids Res, 2006. PMID 17068078, Free PMC Article
  3. DNA as a nutrient: novel role for bacterial competence gene homologs. Finkel SE, et al. J Bacteriol, 2001 Nov. PMID 11591672, Free PMC Article
  4. Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. Palchevskiy V, et al. J Bacteriol, 2006 Jun. PMID 16707682, Free PMC Article
  5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within DNA catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within carbon utilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Preferred Names
DNA utilization protein HofM

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3521972..3522751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417854.4 DNA utilization protein HofM [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417854.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN3NQN4
    Conserved Domains (1) summary
    COG4972
    Location:15 → 174
    PilM; Tfp pilus assembly protein, ATPase PilM [Cell motility, Extracellular structures]
Nucleotide Protein
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