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yrfG purine nucleotidase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947904, updated on 6-May-2021

Summary

Gene symbol
yrfG
Gene description
purine nucleotidase
Primary source
ASAP:ABE-0011092
Locus tag
b3399
See related
ECOCYC:G7742
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3386
Summary
HAD superfamily. [More information is available at EcoGene: EG12928]. YrfG is a purine nucleotidase belonging to the superfamily of haloacid dehalogenase (HAD)-like hydrolases. [More information is available at EcoCyc: G7742].
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Genomic context

Sequence:
NC_000913.3 (3528669..3529337)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ADP-sugar diphosphatase NudE Neighboring gene inner membrane protein IgaA Neighboring gene heat shock protein Hsp15 Neighboring gene molecular chaperone Hsp33

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 5'-nucleotidase activity IEA
Inferred from Electronic Annotation
more info
 
enables GMP 5'-nucleotidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables IMP 5'-nucleotidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables manganese ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphoglycolate phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables purine nucleosidase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
purine nucleotidase
NP_417858.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3528669..3529337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417858.4 purine nucleotidase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417858.4

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P64636
    Conserved Domains (1) summary
    PRK14988
    Location:1222
    PRK14988; GMP/IMP nucleotidase; Provisional
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