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hofO DNA utilization protein HofO [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947899, updated on 26-Mar-2025

Summary

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Official Symbol
hofO
Official Full Name
DNA utilization protein HofO
Primary source
ECOCYC:G7737
Locus tag
b3393
See related
ASAP:ABE-0011075
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3380; yrfB
Summary
The yrfB gene product is required for utilization of DNA as the sole source of carbon and energy; yrfB is homologous to genes involved in natural competence and genetic transformation in other bacteria . [More information is available at EcoCyc: G7737].
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Genomic context

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Sequence:
NC_000913.3 (3521009..3521449, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene shikimate kinase 1 Neighboring gene DNA utilization protein HofQ Neighboring gene DNA utilization protein HofP Neighboring gene DNA utilization protein HofN Neighboring gene DNA utilization protein HofM Neighboring gene peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PpdD type IV pilin of Escherichia coli K-12 can Be assembled into pili in Pseudomonas aeruginosa. Sauvonnet N, et al. J Bacteriol, 2000 Feb. PMID 10633126, Free PMC Article
  2. DNA as a nutrient: novel role for bacterial competence gene homologs. Finkel SE, et al. J Bacteriol, 2001 Nov. PMID 11591672, Free PMC Article
  3. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article
  4. Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. Palchevskiy V, et al. J Bacteriol, 2006 Jun. PMID 16707682, Free PMC Article
  5. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within DNA catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within carbon utilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
DNA utilization protein HofO

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3521009..3521449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417852.1 DNA utilization protein HofO [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417852.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7K044
Nucleotide Protein
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