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hofN DNA utilization protein HofN [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947898, updated on 1-May-2025
Official Symbol
hofN
Official Full Name
DNA utilization protein HofN
Primary source
ECOCYC:G7738
Locus tag
b3394
See related
ASAP:ABE-0011077
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3381; yrfC
Summary
The yrfC gene product is required for utilization of DNA as the sole source of carbon and energy; yrfC is homologous to genes involved in natural competence and genetic transformation in other bacteria . [More information is available at EcoCyc: G7738].
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Sequence:
NC_000913.3 (3521433..3521972, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene shikimate kinase 1 Neighboring gene DNA utilization protein HofQ Neighboring gene DNA utilization protein HofP Neighboring gene DNA utilization protein HofO Neighboring gene DNA utilization protein HofM Neighboring gene peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase MrcA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. PpdD type IV pilin of Escherichia coli K-12 can Be assembled into pili in Pseudomonas aeruginosa. Sauvonnet N, et al. J Bacteriol, 2000 Feb. PMID 10633126, Free PMC Article
  2. DNA as a nutrient: novel role for bacterial competence gene homologs. Finkel SE, et al. J Bacteriol, 2001 Nov. PMID 11591672, Free PMC Article
  3. Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. Palchevskiy V, et al. J Bacteriol, 2006 Jun. PMID 16707682, Free PMC Article
  4. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
  5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within DNA catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within carbon utilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA utilization protein HofN

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3521433..3521972 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417853.1 DNA utilization protein HofN [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417853.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    W1ETT8
    Conserved Domains (1) summary
    COG3166
    Location:3 → 179
    PilN; Tfp pilus assembly protein PilN [Cell motility, Extracellular structures]
Nucleotide Protein
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