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trpS tryptophan--tRNA ligase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947894, updated on 3-Dec-2024

Summary

Official Symbol
trpS
Official Full Name
tryptophan--tRNA ligase
Primary source
ECOCYC:EG11030
Locus tag
b3384
See related
ASAP:ABE-0011056
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3371
Summary
Tryptophanyl-tRNA synthetase (TrpRS) is a member of the family of aminoacyl-tRNA synthetases, which interpret the genetic code by covalently linking amino acids to their specific tRNA molecules. [More information is available at EcoCyc: EG11030].
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Genomic context

Sequence:
NC_000913.3 (3512634..3513638, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PRD domain-containing protein YhfY Neighboring gene putative DNA-binding transcriptional regulator YhfZ Neighboring gene phosphoglycolate phosphatase Neighboring gene ribulose-phosphate 3-epimerase Neighboring gene DNA adenine methyltransferase

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables tryptophan-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables tryptophan-tRNA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables tryptophan-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in tryptophanyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tryptophanyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within tryptophanyl-tRNA aminoacylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol EXP
Inferred from Experiment
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
tryptophan--tRNA ligase
NP_417843.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3512634..3513638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417843.1 tryptophan--tRNA ligase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417843.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN5JBG9
    Conserved Domains (1) summary
    PRK00927
    Location:3333
    PRK00927; tryptophanyl-tRNA synthetase; Reviewed