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frlR DNA-binding transcriptional regulator FrlR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947885, updated on 30-Jul-2025
Official Symbol
frlR
Official Full Name
DNA-binding transcriptional regulator FrlR
Primary source
ECOCYC:G7727
Locus tag
b3375
See related
ASAP:ABE-0011031
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3362; yhfR
Summary
YhfR may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes . [More information is available at EcoCyc: G7727].
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Sequence:
NC_000913.3 (3504052..3504783)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene fructoselysine 6-phosphate deglycase Neighboring gene fructoselysine 3-epimerase Neighboring gene fructoselysine 6-kinase Neighboring gene putative aminotransferase YhfS Neighboring gene uncharacterized protein YhfT

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of glucoselysine-6-phosphate deglycase, an enzyme involved in the metabolism of the fructation product glucoselysine. Wiame E, et al. Biochem J, 2005 Dec 1. PMID 16153181, Free PMC Article
  2. Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli. Wiame E, et al. J Biol Chem, 2002 Nov 8. PMID 12147680
  3. The repertoire of DNA-binding transcriptional regulators in Escherichia coli K-12. Pérez-Rueda E, et al. Nucleic Acids Res, 2000 Apr 15. PMID 10734204, Free PMC Article
  4. Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea. Pérez-Rueda E, et al. Comput Biol Chem, 2004 Dec. PMID 15556475
  5. Interaction network containing conserved and essential protein complexes in Escherichia coli. Butland G, et al. Nature, 2005 Feb 3. PMID 15690043

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional regulator FrlR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3504052..3504783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417834.6 DNA-binding transcriptional regulator FrlR

    See identical proteins and their annotated locations for NP_417834.6

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1X3JBB0, A0A979GI11, J7R9Z6
    Conserved Domains (1) summary
    PRK11402
    Location:3 → 243
    PRK11402; transcriptional regulator PhoB
Nucleotide Protein
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