U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nirB nitrite reductase (NADH) large subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947868, updated on 10-Feb-2026
Official Symbol
nirB
Official Full Name
nitrite reductase (NADH) large subunit
Primary source
ECOCYC:EG10653
Locus tag
b3365
See related
ASAP:ABE-0011003
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3353
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (3494011..3496554)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene peptidyl-prolyl cis-trans isomerase A Neighboring gene putative transporter TsgA Neighboring gene nitrite reductase (NADH) small subunit Neighboring gene nitrite transporter NirC Neighboring gene siroheme synthase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables heme binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nitrite reductase (NADH) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nitrite reductase (NADH) activity IEA
Inferred from Electronic Annotation
more info
  
enables nitrite reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in energy derivation by oxidation of organic compounds IEA
Inferred from Electronic Annotation
more info
  
involved_in nitrate assimilation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nitrate assimilation IEA
Inferred from Electronic Annotation
more info
  
involved_in nitrate assimilation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of nitrite reductase complex [NAD(P)H] IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
nitrite reductase (NADH) large subunit
NP_417824.1

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3494011..3496554
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417824.1 nitrite reductase (NADH) large subunit

    See identical proteins and their annotated locations for NP_417824.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376FVP2, A0A8S7BDP9, A0A8S7I281, A0AAN3TSJ6
    Conserved Domains (1) summary
    PRK14989
    Location:1 → 847
    PRK14989; nitrite reductase subunit NirD; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.