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chiA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947837, updated on 11-Sep-2024

Summary

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Official Symbol
chiA
Primary source
ECOCYC:EG11237
Locus tag
b3338
See related
ASAP:ABE-0010909
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3325; yheB
Summary
A purified fragment of ChiA binds to chitin with high affinity, but binds only poorly to cellulose . [More information is available at EcoCyc: EG11237].
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Genomic context

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Sequence:
NC_000913.3 (3467160..3469853, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene bacterioferritin Neighboring gene bacterioferritin-associated ferredoxin Neighboring gene translation elongation factor Tu 1 Neighboring gene elongation factor G

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The ChiA (YheB) protein of Escherichia coli K-12 is an endochitinase whose gene is negatively controlled by the nucleoid-structuring protein H-NS. Francetic O, et al. Mol Microbiol, 2000 Mar. PMID 10760150
  2. Functional analysis of the carbohydrate-binding domains of Erwinia chrysanthemi Cel5 (Endoglucanase Z) and an Escherichia coli putative chitinase. Simpson HD, et al. J Bacteriol, 1999 Aug. PMID 10419961, Free PMC Article
  3. Chitin, Chitin Oligosaccharide, and Chitin Disaccharide Metabolism of Escherichia coli Revisited: Reassignment of the Roles of ChiA, ChbR, ChbF, and ChbG. Walter A, et al. Microb Physiol, 2021. PMID 33794535
  4. Cloning, sequencing, and mapping of the bacterioferritin gene (bfr) of Escherichia coli K-12. Andrews SC, et al. J Bacteriol, 1989 Jul. PMID 2661540, Free PMC Article
  5. Role of the Escherichia coli Tat pathway in outer membrane integrity. Ize B, et al. Mol Microbiol, 2003 Jun. PMID 12787348

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables chitin binding IEA
Inferred from Electronic Annotation
more info
  
enables chitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables endochitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables endochitinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
enables lysozyme activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in chitin catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in polysaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
endochitinase
NP_417797.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3467160..3469853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417797.1 endochitinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417797.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAI9MEB6
    Conserved Domains (3) summary
    cd06543
    Location:587 → 892
    GH18_PF-ChiA-like; PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in ...
    smart00495
    Location:128 → 173
    ChtBD3; Chitin-binding domain type 3
    cd12215
    Location:461 → 509
    ChiC_BD; Chitin-binding domain of chitinase C
Nucleotide Protein
Heading Accession and Version

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