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chiA endochitinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947837, updated on 6-May-2021

Summary

Gene symbol
chiA
Gene description
endochitinase
Primary source
ASAP:ABE-0010909
Locus tag
b3338
See related
ECOCYC:EG11237
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3325; yheB
Summary
A purified fragment of ChiA binds to chitin with high affinity, but binds only poorly to cellulose . [More information is available at EcoCyc: EG11237].
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Genomic context

Sequence:
NC_000913.3 (3467160..3469853, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene bacterioferritin Neighboring gene bacterioferritin-associated ferredoxin Neighboring gene translation elongation factor Tu 1 Neighboring gene elongation factor G

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables chitin binding IEA
Inferred from Electronic Annotation
more info
 
enables chitinase activity IEA
Inferred from Electronic Annotation
more info
 
enables endochitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables endochitinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 
enables lysozyme activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within chitin catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within polysaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3467160..3469853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417797.1 endochitinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417797.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P13656
    Conserved Domains (3) summary
    cd06543
    Location:587892
    GH18_PF-ChiA-like; PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in ...
    smart00495
    Location:128173
    ChtBD3; Chitin-binding domain type 3
    cd12215
    Location:461509
    ChiC_BD; Chitin-binding domain of chitinase C
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