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rplC 50S ribosomal subunit protein L3 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947817, updated on 26-Mar-2025
Official Symbol
rplC
Official Full Name
50S ribosomal subunit protein L3
Primary source
ECOCYC:EG10866
Locus tag
b3320
See related
ASAP:ABE-0010860
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3307
Summary
The L3 protein is a component of the 50S subunit of the ribosome. [More information is available at EcoCyc: EG10866].
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Sequence:
NC_000913.3 (3452297..3452926, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 50S ribosomal subunit protein L2 Neighboring gene 50S ribosomal subunit protein L23 Neighboring gene 50S ribosomal subunit protein L4 Neighboring gene 30S ribosomal subunit protein S10 Neighboring gene putative general secretion pathway protein B

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Resistance to the peptidyl transferase inhibitor tiamulin caused by mutation of ribosomal protein l3. Bøsling J, et al. Antimicrob Agents Chemother, 2003 Sep. PMID 12936991, Free PMC Article
  2. The primary structure of ribosomal protein L3 from Escherichia coli 70 S ribosomes. Muranova TA, et al. FEBS Lett, 1978 Dec 15. PMID 365579
  3. Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center. Long KS, et al. Antimicrob Agents Chemother, 2006 Apr. PMID 16569865, Free PMC Article
  4. Genetics of ribosomal protein methylation in Escherichia coli. II. A mutant lacking a new type of methylated amino acid, N5-methylglutamine, in protein L3. Lhoest J, et al. Mol Gen Genet, 1977 Jul 20. PMID 331083
  5. Polarity of amber mutations in ribosomal protein genes of Escherichia coli. Cabezón T, et al. J Bacteriol, 1980 Jan. PMID 6986365, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: A method for the chemical generation of N-terminal peptide sequence tags for rapid protein identification.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in ribosomal large subunit assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
50S ribosomal subunit protein L3

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3452297..3452926 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417779.1 50S ribosomal subunit protein L3 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417779.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376FT85, A0A775YX50
    Conserved Domains (1) summary
    PRK00001
    Location:1 → 209
    rplC; 50S ribosomal protein L3; Validated
Nucleotide Protein
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