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rpoA RNA polymerase subunit alpha [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947794, updated on 2-May-2024

Summary

Gene symbol
rpoA
Gene description
RNA polymerase subunit alpha
Primary source
ASAP:ABE-0010802
Locus tag
b3295
See related
ECOCYC:EG10893
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3282; pez; phs; sez
Summary
HT_Cmplx11_Mem: [More information is available at EcoGene: EG10893]. RpoA is the subunit of the RNA polymerase core enzyme. [More information is available at EcoCyc: EG10893].
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Genomic context

Sequence:
NC_000913.3 (3440040..3441029, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF1992 domain-containing protein YhdN Neighboring gene 50S ribosomal subunit protein L17 Neighboring gene 30S ribosomal subunit protein S4 Neighboring gene 30S ribosomal subunit protein S11

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA-templated transcription initiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in DNA-templated transcription initiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in bacterial-type flagellum assembly NAS
Non-traceable Author Statement
more info
PubMed 
involved_in bacterial-type flagellum-dependent cell motility NAS
Non-traceable Author Statement
more info
PubMed 
involved_in cell motility NAS
Non-traceable Author Statement
more info
PubMed 
involved_in cellular response to cell envelope stress NAS
Non-traceable Author Statement
more info
PubMed 
involved_in intracellular iron ion homeostasis NAS
Non-traceable Author Statement
more info
PubMed 
involved_in nitrate assimilation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in regulation of DNA-templated transcription elongation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in regulation of DNA-templated transcription initiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of DNA-templated transcription initiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in response to heat NAS
Non-traceable Author Statement
more info
PubMed 
involved_in submerged biofilm formation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in transcription antitermination IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
part_of cytosolic DNA-directed RNA polymerase complex IPI
Inferred from Physical Interaction
more info
PubMed 
part_of cytosolic DNA-directed RNA polymerase complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in membrane HDA PubMed 
part_of transcription elongation factor complex NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
RNA polymerase subunit alpha
NP_417754.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3440040..3441029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417754.1 RNA polymerase subunit alpha [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417754.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AW69
    Conserved Domains (1) summary
    PRK05182
    Location:6316
    PRK05182; DNA-directed RNA polymerase subunit alpha; Provisional