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trkA NAD-binding component of Trk potassium transporters [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947788, updated on 9-Mar-2022

Summary

Gene symbol
trkA
Gene description
NAD-binding component of Trk potassium transporters
Primary source
ASAP:ABE-0010787
Locus tag
b3290
See related
ECOCYC:EG11019
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3276
Summary
Although normally required for Trk activity, overproduction of TrkG or TrkH alone increases K+ transport in a trkA mutant strain (Buurman, 2004). [More information is available at EcoGene: EG11019]. trkA mutants were identified in a kdp background as requiring significantly elevated levels of K+ for growth . trkA encodes part of a K+ transport system . [More information is available at EcoCyc: EG11019].
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Genomic context

Sequence:
NC_000913.3 (3436518..3437894)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase Neighboring gene 16S rRNA m(5)C967 methyltransferase Neighboring gene large conductance mechanosensitive channel Neighboring gene alternative ribosome-rescue factor A Neighboring gene DNA-binding transcriptional activator ZntR

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables NAD binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables potassium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in ion transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within potassium ion transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in potassium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in extrinsic component of cytoplasmic side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NAD-binding component of Trk potassium transporters

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3436518..3437894
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417748.1 NAD-binding component of Trk potassium transporters [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417748.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AGI8
    Conserved Domains (1) summary
    PRK09496
    Location:1456
    trkA; Trk system potassium transporter TrkA