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mlaE intermembrane phospholipid transport system, integral membrane subunit MlaE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947732, updated on 23-Nov-2023

Summary

Gene symbol
mlaE
Gene description
intermembrane phospholipid transport system, integral membrane subunit MlaE
Primary source
ASAP:ABE-0010495
Locus tag
b3194
See related
ECOCYC:EG12800
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3183; yrbE
Summary
YrbE is in an operon with ABC transporter homologs and may be a permease protein. [More information is available at EcoGene: EG12800]. Yrbe is the membrane component of a predicted ABC superfamily toluene efflux transporter. [More information is available at EcoCyc: EG12800].
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Genomic context

Sequence:
NC_000913.3 (3338466..3339248, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene intermembrane phospholipid transport system protein MlaB Neighboring gene intermembrane phospholipid transport system - periplasmic binding protein Neighboring gene intermembrane phospholipid transport system, substrate binding protein MlaD Neighboring gene intermembrane phospholipid transport system, ATP binding subunit MlaF Neighboring gene putative transport protein YrbG

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables phospholipid transfer activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phospholipid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within intermembrane phospholipid transfer IDA
Inferred from Direct Assay
more info
PubMed 
involved_in phospholipid transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in phospholipid transport NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of phospholipid-translocating ATPase complex IPI
Inferred from Physical Interaction
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
intermembrane phospholipid transport system, integral membrane subunit MlaE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3338466..3339248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417661.1 intermembrane phospholipid transport system, integral membrane subunit MlaE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417661.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A418GXL1, A0A7A6NPI5
    Conserved Domains (1) summary
    NF033619
    Location:7259
    perm_MlaE_1; lipid asymmetry maintenance ABC transporter permease subunit MlaE