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lptB lipopolysaccharide transport system ATP binding protein LptB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947725, updated on 9-Mar-2022

Summary

Gene symbol
lptB
Gene description
lipopolysaccharide transport system ATP binding protein LptB
Primary source
ASAP:ABE-0010512
Locus tag
b3201
See related
ECOCYC:EG11680
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3190; yhbG
Summary
LptB depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. [More information is available at EcoGene: EG11680]. LptB is an ATP-binding component of the LptAB-YrbK ABC transporter. [More information is available at EcoCyc: EG11680].
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Genomic context

Sequence:
NC_000913.3 (3343944..3344669)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC Neighboring gene lipopolysaccharide transport system protein LptC Neighboring gene lipopolysaccharide transport system protein LptA Neighboring gene RNA polymerase sigma factor RpoN Neighboring gene ribosome hibernation-promoting factor

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within lipopolysaccharide transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of transporter complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
lipopolysaccharide transport system ATP binding protein LptB
NP_417668.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3343944..3344669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417668.1 lipopolysaccharide transport system ATP binding protein LptB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417668.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A9V1
    Conserved Domains (1) summary
    PRK10895
    Location:1241
    PRK10895; lipopolysaccharide ABC transporter ATP-binding protein; Provisional