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rlmE 23S rRNA 2'-O-ribose U2552 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947689, updated on 5-Sep-2021

Summary

Gene symbol
rlmE
Gene description
23S rRNA 2'-O-ribose U2552 methyltransferase
Primary source
ASAP:ABE-0010447
Locus tag
b3179
See related
ECOCYC:EG11507
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3168; ftsJ; mrsF; rrmJ
Summary
RlmE is the methyltransferase responsible for methylation of 23S rRNA at the 2'-O position of the ribose at the universally conserved U2552 nucleotide . [More information is available at EcoCyc: EG11507].
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Genomic context

Sequence:
NC_000913.3 (3327035..3327664, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoglucosamine mutase Neighboring gene dihydropteroate synthase Neighboring gene ATP-dependent zinc metalloprotease FtsH Neighboring gene ribosome assembly factor YhbY Neighboring gene transcription elongation factor GreA

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables RNA methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables rRNA (uridine) methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables rRNA (uridine-2'-O-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables rRNA (uridine-2'-O-)-methyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables rRNA (uridine-2'-O-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in RNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within RNA methylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within enzyme-directed rRNA 2'-O-methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ribosomal large subunit assembly IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
23S rRNA 2'-O-ribose U2552 methyltransferase
NP_417646.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3327035..3327664 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417646.1 23S rRNA 2'-O-ribose U2552 methyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417646.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0C0R7
    Conserved Domains (1) summary
    PRK11188
    Location:1208
    rrmJ; 23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE
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