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pnp polynucleotide phosphorylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947672, updated on 19-Sep-2024

Summary

Official Symbol
pnp
Official Full Name
polynucleotide phosphorylase
Primary source
ECOCYC:EG10743
Locus tag
b3164
See related
ASAP:ABE-0010397
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
bfl; ECK3152
Summary
Cold induction occurs by reversal of post-translational autoregulation. [More information is available at EcoGene: EG10743]. Polynucleotide phosphorylase (PNPase) is a 3' to 5' exonuclease and a 3'-terminal oligonucleotide polymerase. [More information is available at EcoCyc: EG10743].
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Genomic context

Sequence:
NC_000913.3 (3309033..3311168, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase DeaD Neighboring gene uncharacterized protein YrbN Neighboring gene lipoprotein NlpI Neighboring gene ncRNA Neighboring gene 30S ribosomal subunit protein S15

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 3'-5'-RNA exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 3'-5'-RNA exonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA binding EXP
Inferred from Experiment
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables cyclic-di-GMP binding IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables polyribonucleotide nucleotidyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables polyribonucleotide nucleotidyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables polyribonucleotide nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in RNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in RNA catabolic process NAS
Non-traceable Author Statement
more info
PubMed 
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in RNA processing NAS
Non-traceable Author Statement
more info
PubMed 
involved_in mRNA catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to heat IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of bacterial degradosome IPI
Inferred from Physical Interaction
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane HDA PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
polynucleotide phosphorylase
NP_417633.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3309033..3311168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417633.4 polynucleotide phosphorylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417633.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7QZ98
    Conserved Domains (1) summary
    PRK11824
    Location:1692
    PRK11824; polynucleotide phosphorylase/polyadenylase; Provisional