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kbaY tagatose-1,6-bisphosphate aldolase 1 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947644, updated on 4-Feb-2026
Official Symbol
kbaY
Official Full Name
tagatose-1,6-bisphosphate aldolase 1
Primary source
ECOCYC:EG12768
Locus tag
b3137
See related
ASAP:ABE-0010307
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
agaY; ECK3125; kba; yraC
Summary
Part of aga cluster. kbaY, gatY, fbaA and ydjI are paralogs. [More information is available at EcoGene: EG12768].
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Sequence:
NC_000913.3 (3283143..3284003)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene putative galactosamine-6-phosphate deaminase/isomerase Neighboring gene cryptic galactosamine-specific PTS enzyme IIB component Neighboring gene cryptic galactosamine-specific PTS enzyme IIC component Neighboring gene cryptic galactosamine-specific PTS enzyme IID component

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Analysis of mutations affecting the dissmilation of galactitol (dulcitol) in Escherichia coli K 12. Lengeler J. Mol Gen Genet, 1977 Mar 28. PMID 325390
  2. Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli. Nobelmann B, et al. Biochim Biophys Acta, 1995 May 17. PMID 7772602
  3. The genes and enzymes for the catabolism of galactitol, D-tagatose, and related carbohydrates in Klebsiella oxytoca M5a1 and other enteric bacteria display convergent evolution. Shakeri-Garakani A, et al. Mol Genet Genomics, 2004 Jul. PMID 15257457
  4. Temporal gene-expression in Escherichia coli K-12 biofilms. Domka J, et al. Environ Microbiol, 2007 Feb. PMID 17222132
  5. Structure of tagatose-1,6-bisphosphate aldolase. Insight into chiral discrimination, mechanism, and specificity of class II aldolases. Hall DR, et al. J Biol Chem, 2002 Jun 14. PMID 11940603

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aldehyde-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables tagatose-bisphosphate aldolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tagatose-bisphosphate aldolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables tagatose-bisphosphate aldolase activity IEA
Inferred from Electronic Annotation
more info
  
enables tagatose-bisphosphate aldolase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-tagatose 6-phosphate catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in D-tagatose 6-phosphate catabolic process NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein homotetramerization IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
tagatose-1,6-bisphosphate aldolase 1
NP_417606.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3283143..3284003
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417606.1 tagatose-1,6-bisphosphate aldolase 1

    See identical proteins and their annotated locations for NP_417606.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9KIP8
    UniProtKB/TrEMBL
    A0A3L5H3Q5
    Conserved Domains (1) summary
    PRK12738
    Location:1 → 286
    kbaY; tagatose-bisphosphate aldolase subunit KbaY
Nucleotide Protein
Heading Accession and Version

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