U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

garK glycerate 2-kinase 1 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947632, updated on 30-Jul-2025
Official Symbol
garK
Official Full Name
glycerate 2-kinase 1
Primary source
ECOCYC:EG11175
Locus tag
b3124
See related
ASAP:ABE-0010271
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3112; yhaD
Summary
Glycerate kinase I (GKI), encoded by garK, catalyzes the formation of 2-phosphoglycerate from D-glycerate . [More information is available at EcoCyc: EG11175].
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (3270625..3271770, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YhaC Neighboring gene ncRNA Neighboring gene tartronate semialdehyde reductase Neighboring gene alpha-dehydro-beta-deoxy-D-glucarate aldolase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. An in vivo metabolic approach for deciphering the product specificity of glycerate kinase proves that both E. coli's glycerate kinases generate 2-phosphoglycerate. Zelcbuch L, et al. PLoS One, 2015. PMID 25823014, Free PMC Article
  2. Precise mapping of the rnpB gene encoding the RNA component of RNase P in Escherichia coli K-12. Komine Y, et al. J Bacteriol, 1991 Mar. PMID 1705543, Free PMC Article
  3. Processing of the precursor to the catalytic RNA subunit of RNase P from Escherichia coli. Lundberg U, et al. RNA, 1995 May. PMID 7489504, Free PMC Article
  4. Two forms of D-glycerate kinase in Escherichia coli. Ornston MK, et al. J Bacteriol, 1969 Mar. PMID 4887503, Free PMC Article
  5. A common regulator for the operons encoding the enzymes involved in D-galactarate, D-glucarate, and D-glycerate utilization in Escherichia coli. Monterrubio R, et al. J Bacteriol, 2000 May. PMID 10762278, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables glycerate 2-kinase activity EXP
Inferred from Experiment
more info
 PubMed 
enables glycerate 2-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycerate 2-kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glycerate 2-kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycerate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within D-glucarate catabolic process IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in carboxylic acid catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within galactarate catabolic process IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in organic acid phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
glycerate 2-kinase 1
NP_417593.4

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3270625..3271770 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417593.4 glycerate 2-kinase 1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8T6PTW0
    Conserved Domains (1) summary
    PRK10342
    Location:1 → 381
    PRK10342; glycerate kinase I; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.