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exuR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947602, updated on 11-Sep-2024

Summary

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Official Symbol
exuR
Primary source
ECOCYC:EG12739
Locus tag
b3094
See related
ASAP:ABE-0010176
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3085
Summary
ExuR is an HTH GntR-type DNA-binding transcriptional regulator. [More information is available at EcoGene: EG12739]. The Exuronate repressor," ExuR, is a DNA-binding transcription factor that negatively regulates its own synthesis and represses transcription of the operons involved in transport and catabolism of galacturonate and glucuronate . [More information is available at EcoCyc: EG12739].
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Genomic context

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Sequence:
NC_000913.3 (3246652..3247428)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-glucoronate/D-galacturonate isomerase Neighboring gene hexuronate transporter Neighboring gene protein YqiM Neighboring gene DedA family protein YqjA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation and transcription direction of exuR, a self-regulated repressor in escherichia coli K-12. Hugovieux-Cotte-Pattat N, et al. J Mol Biol, 1982 Mar 25. PMID 6808145
  2. Genetic analysis of uxuR and exuR genes: evidence for ExuR and UxuR monomer repressors interactions. Ritzenthaler P, et al. Mol Gen Genet, 1985. PMID 3929016
  3. Control of hexuronate metabolism in Escherichia coli by the two interdependent regulators, ExuR and UxuR: derepression by heterodimer formation. Tutukina MN, et al. Microbiology (Reading), 2016 Jul. PMID 27129867
  4. Interchangeability of repressors for the control of the uxu and uid operons in E. coli K12. Ritzenthaler P, et al. Mol Gen Genet, 1983. PMID 6353163
  5. Role of the b subunit of the Escherichia coli proton-translocating ATPase. A mutagenic analysis. Porter AC, et al. J Biol Chem, 1985 Jul 5. PMID 2861200

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-binding transcriptional repressor ExuR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3246652..3247428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417565.2 DNA-binding transcriptional repressor ExuR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417565.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7A6WUT7
    Conserved Domains (1) summary
    PRK11523
    Location:1 → 253
    PRK11523; transcriptional regulator ExuR
Nucleotide Protein
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