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rpsU 30S ribosomal subunit protein S21 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947577, updated on 6-Jul-2026
Official Symbol
rpsU
Official Full Name
30S ribosomal subunit protein S21
Primary source
ECOCYC:EG10920
Locus tag
b3065
See related
ASAP:ABE-0010063
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3055
Summary
rpsU has been shown to be an essential gene (Bubunenko, 2007). [More information is available at EcoGene: EG10920]. The S21 protein is a component of the 30S subunit of the ribosome. [More information is available at EcoCyc: EG10920].
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Sequence:
NC_000913.3 (3210781..3210996)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-tartrate:succinate antiporter Neighboring gene N(6)-L-threonylcarbamoyladenine synthase, TsaD subunit Neighboring gene DNA primase Neighboring gene RNA polymerase sigma factor RpoD

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The function of ribosomal protein S21 in protein synthesis. Van Duin J, et al. Eur J Biochem, 1981 Sep 1. PMID 7028483
  2. Determination of the complete amino acid sequence of protein S21 from Escherichia coli ribosomes. Vandekerckhove J, et al. Hoppe Seylers Z Physiol Chem, 1975 Dec. PMID 765257
  3. Fluorescence study of the topology of messenger RNA bound to the 30S ribosomal subunit of Escherichia coli. Czworkowski J, et al. Biochemistry, 1991 May 14. PMID 2029524
  4. Nucleotide sequence of the rpsU-dnaG-rpoD operon from Salmonella typhimurium and a comparison of this sequence with the homologous operon of Escherichia coli. Erickson BD, et al. Gene, 1985. PMID 3005129
  5. Ribosomal protein S21 is required for full activity in the initiation of protein synthesis. Held WA, et al. Mol Gen Genet, 1974. PMID 4595779

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Determination of the complete amino acid sequence of protein S21 from Escherichia coli ribosomes.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in ribosomal small subunit assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
30S ribosomal subunit protein S21

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3210781..3210996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417537.1 30S ribosomal subunit protein S21

    See identical proteins and their annotated locations for NP_417537.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P68679
    Conserved Domains (1) summary
    PRK00270
    Location:1 → 64
    rpsU; 30S ribosomal protein S21; Reviewed
Nucleotide Protein
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