U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ttdA L(+)-tartrate dehydratase subunit alpha [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947565, updated on 25-Jun-2025
Official Symbol
ttdA
Official Full Name
L(+)-tartrate dehydratase subunit alpha
Primary source
ECOCYC:EG11168
Locus tag
b3061
See related
ASAP:ABE-0010050
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3051; ygjA
Summary
The ttdA gene encodes the alpha subunit of the L-tartrate dehydratase enzyme and is expressed in exponentially growing cells . [More information is available at EcoCyc: EG11168].
NEW
Try the new Gene table
Try the new Transcript table
Sequence:
NC_000913.3 (3206463..3207374)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative glycerol-3-phosphate acyltransferase Neighboring gene DNA-binding transcriptional activator Dan Neighboring gene L(+)-tartrate dehydratase subunit beta Neighboring gene L-tartrate:succinate antiporter Neighboring gene N(6)-L-threonylcarbamoyladenine synthase, TsaD subunit

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of the L-tartrate dehydratase genes (ttdA and ttdB) of Escherichia coli and evolutionary relationship with the class I fumarase genes. Reaney SK, et al. J Gen Microbiol, 1993 Jul. PMID 8371115
  2. Regulation of tartrate metabolism by TtdR and relation to the DcuS-DcuR-regulated C4-dicarboxylate metabolism of Escherichia coli. Kim OB, et al. Microbiology (Reading), 2009 Nov. PMID 19661178
  3. Possible new genes as revealed by molecular analysis of a 5-kb Escherichia coli chromosomal region 5' to the rpsU-dnaG-rpoD macromolecular-synthesis operon. Nesin M, et al. Gene, 1987. PMID 3297921
  4. The L-tartrate/succinate antiporter TtdT (YgjE) of L-tartrate fermentation in Escherichia coli. Kim OB, et al. J Bacteriol, 2007 Mar. PMID 17172328, Free PMC Article
  5. The SWISS-PROT protein sequence data bank, recent developments. Bairoch A, et al. Nucleic Acids Res, 1993 Jul 1. PMID 8332529, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables fumarate hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within single-species biofilm formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tartrate catabolic process NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within tartrate metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of catalytic complex NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
L(+)-tartrate dehydratase subunit alpha
NP_417533.1

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3206463..3207374
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417533.1 L(+)-tartrate dehydratase subunit alpha [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417533.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN5FRY2
    Conserved Domains (1) summary
    PRK08230
    Location:6 → 303
    PRK08230; tartrate dehydratase subunit alpha; Validated
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.