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parC DNA topoisomerase IV, subunit A [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947499, updated on 22-May-2018

Summary

Gene symbol
parC
Gene description
DNA topoisomerase IV, subunit A
Primary source
EcoGene:EG10686
Locus tag
b3019
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3010; JW2987
Summary
ParC physically interacts with SeqA. [More information is available at EcoGene: EG10686]. The purified ParC protein is a dimer in solution . [More information is available at EcoCyc: EG10686].

Genomic context

Sequence:
NC_000913.3 (3163715..3165973, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene septal ring component that protects the divisome from stress; multicopy suppressor of ftsI(Ts) Neighboring gene 1-acyl-sn-glycerol-3-phosphate acyltransferase Neighboring gene putative ABC transporter permease Neighboring gene antitoxin for MqsR toxin; transcriptional repressor

Bibliography

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
Contributes_to DNA topoisomerase activity IDA
Inferred from Direct Assay
more info
PubMed 
CONTRIBUTES_TO DNA topoisomerase type II (ATP-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Contributes_to DNA topoisomerase type II (ATP-hydrolyzing) activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA topoisomerase type II (ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA topological change IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA topological change IDA
Inferred from Direct Assay
more info
PubMed 
DNA topological change IEA
Inferred from Electronic Annotation
more info
 
chromosome segregation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromosome segregation IDA
Inferred from Direct Assay
more info
PubMed 
chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
plasmid partitioning IDA
Inferred from Direct Assay
more info
PubMed 
sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
DNA topoisomerase complex (ATP-hydrolyzing) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA topoisomerase complex (ATP-hydrolyzing) IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
extrinsic component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Names
DNA topoisomerase IV, subunit A
NP_417491.1
  • DNA topoisomerase IV subunit A

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3163715..3165973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417491.1 DNA topoisomerase IV, subunit A [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417491.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AFI2
    Conserved Domains (2) summary
    TIGR01062
    Location:5738
    parC_Gneg; DNA topoisomerase IV, A subunit, proteobacterial
    sd00041
    Location:499538
    GyrA-ParC_C; GyrA_CTD repeat [structural motif]
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