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thrB homoserine kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947498, updated on 6-May-2021

Summary

Gene symbol
thrB
Gene description
homoserine kinase
Primary source
ASAP:ABE-0000010
Locus tag
b0003
See related
ECOCYC:EG10999
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0003
Summary
Homoserine kinase (ThrB) catalyzes the conversion of homoserine to O-phospho-L-homoserine en route to generating threonine. [More information is available at EcoCyc: EG10999].
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Genomic context

Sequence:
NC_000913.3 (2801..3733)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene thr operon leader peptide Neighboring gene fused aspartate kinase/homoserine dehydrogenase 1 Neighboring gene threonine synthase Neighboring gene DUF2502 domain-containing protein YaaX

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables homoserine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables homoserine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
homoserine kinase
NP_414544.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2801..3733
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414544.1 homoserine kinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414544.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P00547
    Conserved Domains (1) summary
    TIGR00191
    Location:2308
    thrB; homoserine kinase
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